Let's talk about the Brooks Glycerin GTS 22 - a shoe that's got runners either singing its praises or returning them immediately. I've put about 50 miles on these babies, and here's the real deal.
The DNA Tuned cushioning is LEGIT. Those dual-size cells? You can actually feel the difference - plush landings in the heel, snappy toe-offs in the forefoot. It's like walking on responsive clouds... if clouds had structure.
That GuideRails system? Game changer for my overpronation. Felt like my ankles finally had a responsible adult supervising them during runs. But heads up - if you've got wide feet, these might feel like medieval torture devices after hour three.
The double jacquard knit upper breathes better than my last relationship, but runs narrow. Had to go up half a size (and I'm usually dead-on with Brooks sizing). Saw some reviewers at 400lbs loving these - can confirm they handle weight beautifully while staying surprisingly light.
Diabetic certification is a nice bonus - that roomy toe box (when sized right) could save some toes. But Ghost Max fans beware: these feel noticeably more restrictive up front.
Final verdict? If you need serious stability and have narrow-to-normal feet, these could be your holy grail. Wide-footed folks might want to test drive first or check out the Ghost Max instead.